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This case underscores that increased serum autoimmune makers alone do not justify a firm AIH diagnosis, especially given the high prevalence of elevated ANA titers in the general white population in the US, reported to be up to 17.8% [117]

Tracy LE, Minasian RA, Caterson EJ

Because tolerability has not been quantified in humans, there is no evidence-based safe concentration or frequency to point to