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Li JM, Zhang YL, Jin T, Jin ZK, Zhu ML, Qing GC, et al

5.6 Berberine Berberine, an isoquinoline alkaloid (chemical formula C 20 H 18 NO 4 + , molecular weight 336.36 Da), is predominantly isolated from the rhizomes of Coptis chinensis Franch (Ranunculaceae), root bark of Berberis julianae Schneid (Berberidaceae), and bark of Phellodendron amurense Rupr (Rutaceae)