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Mice were anesthetized using a ketamine/xylazine mixture (100 mg/kg ketamine and 10 mg/kg xylazine), administrated by i.p

It is often combined with Momordica charantia , also known as bitter melon

These findings reveal the importance of mTOR in improving tendon structural integrity by promoting type I collagen production, offering a potential therapeutic target for IGF-1 in tendon repair applications