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Description

Astrocytes in the glaucomatous ONH exhibit thickened processes, calcium-dependent hypertrophy and proliferation (86, 99)

Interestingly, it has been found that extramitochondrial Ca 2+ also regulates mitochondrial metabolism

In 2022, WHO recorded that 43% of adults (18 years and above) globally were overweight and 16% were living with obesity

Notably, the ratio of IL-10 to TNF- varies across different tissues, exhibiting an anti-inflammatory impact in muscle while adipose tissue tends to be pro-inflammatory (193)