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To view a copy of this license, visit About this article Cite this article Bidabadi, S.S., VanderWeide, J

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They work in different pathways and actually complement each other

Upon catalysis of COXs, dihomo--linolenic acid (DGLA) and arachidonic acid (AA) can be oxidized by radical-mediated lipid peroxidation and produce prostaglandins, which linking the lipid peroxidation directly to inflammation and apoptotic processes [32,33,34]

Autophagy plays a crucial role in progesterone-mediated reproductive function, as demonstrated by experimental research that shows deletion of autophagy-related proteins, such as FIP200, reduces progesterone responsiveness and causes pathological inflammation [179]