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Immune, primarily antigen-presenting cells of myeloid origin as well as nonimmune cells (Qu et al., 2017) perceive extracellular HSP70 signaling via either C-type lectin or scavenger pattern recognition receptors (PRRs), thereby initiating cytokine release involved in innate immune responses (Murshid et al., 2018)

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Hispanic and Black patients were 28 percent and 29 percent less likely to enroll than white patients after adjustment for incidence, age, and other factors