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We show that GPX4 is downregulated at both gene and protein level in response to NEC, in human intestinal tissue with active NEC and in an in vitro enteroid NEC model

Metformin, through the induction of 5' AMP-activated protein kinase and subsequently insulin sensitivity, has been widely used as a therapeutic agent in various conditions, including type 2 diabetes mellitus, PCOS and gestational diabetes (Reference Rice, Elia and Jawad42)

doi: 10.1155/2021/2915019 45 TanSHouXMeiL

Gln synthetase catalyzes the terminal step in Gln de novo synthesis and is a key enzyme in Gln metabolism [16, 17]

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