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Description

R.ShwabE

Anthocyanins and metabolites resolve TNF--mediated production of E-selectin and adhesion of monocytes to endothelial cells

Furthermore, this approach, creating a multispecific that is bivalent to the target and monovalent to the effector cell, results in a molecule with a mass similar to that of other multispecific antibodies that are already FDA-approved (e.g., Glofitamab) or still being evaluated in clinical trials (e.g., Imvotamab, an IgM-based bispecific)