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Additional synthetic-biology approaches, including tunable ON switches, split CAR designs, and small-molecule-responsive domains, may allow in vivo control of CAR T-cell activity with improved safety [174, 175]

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Here are some examples of how IV therapy can be used

C.SunT.RupprechtG.LinC.-C.HsuD.et al (2019)

Our previous analysis by immunofluorescence microscopy showed that LDHB colocalizes with mitochondria 11 , which is in agreement with a previous study 25