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doi: 10.1016/j.jss.2005.05.028 21 LimJSLeeSHYunHLeeDYChoNYooGet al

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It reduces amyloid-beta plaques in Alzheimers disease, modulates neuroinflammation, and enhances cognitive function by crossing the bloodbrain barrier (29)

A deficiency in vitamin B12 may cause tiredness, weakness, constipation, loss of Vitamin B12, often referred to as the energy vitamin, is an essential vitamin critical to the metabolizing of fats and carbohydrates

Subsequently, all samples were subjected to centrifugation at 1500 rpm for 15 min at 4 C, facilitating a clear delineation of the two phases: the upper (lipophilic) phase, which contains the apolar metabolites, and the lower (hydrophilic) phase, which comprises the polar metabolites of interest