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Randomized, double-blind comparison of 4 mg/kg versus 2 mg/kg intravenous cyclosporine in severe ulcerative colitis1 1Gert Van Assche, Severine Vermeire, Geert DHaens, and Paul Rutgeerts have been instrumental in the design of the study, trial management, data analysis, and writing the paper

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Yet, the scientists also report that a larger study in 536 subjects failed to find any significant weight loss after 24 weeks of daily AOD 9604 use, which led to product discontinuation