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10.1038/s41467-019-13668-3 139 MatobaA.MatsuyamaN.ShibataS.MasakiE.EmalaC

These three pathophysiological pillars are intricately linked through a self-perpetuating redox-endocrine loop that amplifies metabolic and reproductive dysfunction

ACS Appl Nano Mater 1(6):26992708

Epub 2016 Aug 22

however, if the effect of inflammatory factors is too strong and the body is too weak for compensatory adaptive anti-inflammatory mechanisms, the inflammatory process can develop into SIRS [24]