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Real-time imaging indicated that the interval from navigation to treatment initiation was ~260 s, representing a substantial reduction compared with conventional stepwise diagnosis and intervention workflows and minimizing the influence of lesion status changes during the therapeutic window (Fig

To further confirm that the ferroptosis resistance of 4-OI was dependent on Nrf2, the siRNA against Nrf2 was constructed and successfully reduced Nrf2 levels in THP-1 cells (Fig