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Many entities have already announced COVID-19 responses, including for example, Medicago, iBio and Kentucky BioProcessing, all of who set out to develop subunit vaccines 87 ( as well as Plantform and South Africa-based CapeBiopharms, who set out to produce antibodies and test reagents

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Immuno-oncology advances are propelled by three paradigm-shifting modalitiesimmune checkpoint disruption (anti-PD-1/CTLA-4) to reverse T-cell exhaustion, genetically engineered CAR-T cells targeting CD19/BCMA for tumor-specific cytotoxicity, and dendritic cell vaccines loaded with neoantigens to prime antigen-presenting cellswhich collectively overcome tumor immune evasion mechanisms, achieving durable remission rates exceeding 50% in refractory lymphomas (NCT02348216)