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Other Types In addition to the types of natural products mentioned above, many other types such as peptides and proteins, phenylpropanoids, coumarins, and alkaloids also possess numerous bioactivities, which possess potential hemorrhoid improvement capabilities

Receptor activation promotes regulatory T-cell (Treg) differentiation and activity, increases the production of anti-inflammatory cytokines such as interleukin-18 (IL-18), and helps maintain the Th17/Treg balance, thereby attenuating the pro-inflammatory responses characteristic of active IBD [17, 18]

Swartz RD, Wesley JR, Somermeyer G, Lau K

doi: 10.18596/jotcsa.913136 [DOI] [Google Scholar] 33

Safety Considerations and When Provider Guidance Is Essential Glutathione is generally well-tolerated, but excessive supplementation may cause gastrointestinal upset, headaches, or rarely allergic reactions