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23-25 Further, pregnant women risk toxic exposure to the developing fetus since the mobilization of stored lead from the mothers bones can leach into the bloodstream, and this is more likely the result of chronic rather than acute lead exposure in the mother

The Connectivity Map analysis cited by Campbell, Pickart, and Margolina found that GHK affects approximately 31 percent of analyzed human genes, with the net pattern resetting age-shifted gene expression toward younger profiles 8 9

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Folic acid supplementation is recommended during pregnancy due to its prophylactic role, but its influence on women undergoing ART is not as widely recognized

For example, a systematic review and meta-analysis demonstrated that melatonin improved the fertilization rate and the number of mature oocytes (MII), although it did not significantly affect the clinical pregnancy rate (81)