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In a study involving SAH model rats, oral administration of CU (10 mg/kg) over the course of 1 week resulted in a significant reduction in glutamate and GLT-1 expression, with malondialdehyde (MDA) levels in the hippocampus and cortical regions decreasing by 18% and 29%, respectively

Many studies have attempted to address this issue, and we have shown that increasing the glutathione (GSH) content in yeasts confers tolerance towards lignocellulose inhibitors, subsequently increasing the ethanol titres

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Our MD results demonstrated the ability of both n-hexadecanoic acid and L-car to form hydrogen bonds with the ASN226 residue of SIRT1, indication their ability to activate SIRT1 74