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Despite these advantages, some natural antioxidants may have lower individual radical scavenging abilities compared to synthetic alternatives, potentially requiring higher quantities for equivalent effects [121, 122]

Initiation and progression of ossification of the posterior longitudinal ligament of the cervical spine in the hereditary spinal hyperostotic mouse (twy/twy)

101 Furthermore, Aspirin inhibits mitochondrial function, leading to increased ROS production as an outcome of disruption in histone methylation

Zn 2+ , Ni 2+ and Cu 2+ are the most commonly used metal ions

5 Challenges and future directions in microbiota-based interventions for hypothyroidism Although microbiota-targeted strategies present a promising adjunct in the management of hypothyroidism, several critical challenges must be addressed to fully realize their therapeutic potential (Figure 5)