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Description

Due to the incomplete KO of DUSP8, the phenotype of double deficient mice may be a consequence of DUSP6 deficiency

Pathway / Mechanistic Context Ipamorelin is used to probe GHSR-1a-linked GPCR signaling in which receptor engagement can trigger calcium mobilization and modulation of adenylate cyclase activity, leading to downstream phosphorylation events and transcriptional responses