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Research published in Science Direct found that nutritional deficiencies were diagnosed in 12.7% of patients within six months of starting GLP-1 receptor agonist therapy, and that number climbed to 22.4% within twelve months

Overall, we conclude that PC patients with low expression of VRK2 are sensitive to GSH-targeting therapy, while PC patients with high expression of VRK2 are re-sensitive to GSH-targeting therapy following VRK2 inhibition, indicating genetic aberrance of VRK2 expression stratifies the response of PC to metabolism-targeted therapies