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Jarosz M, Olbert M, Wyszogrodzka G, Myniec K, Librowski T

Similarly, combined analysis of the 165 ROS-associated genes with the 3352 downregulated DEGs revealed 22 candidate ROS-associated downregulated DEGs in COAD, including LRPK2, TLR6, CYBB, ATP7A, HIF1A, CD36, CYP1B1, P2RX7, NOX4, TLR2, SH3PXD2A, BCL2, AGTR1, FBLN5, PDK4, THBS1, ITGAM, PDGFRB, EDN1, LEP, SFTPD, and MAPT

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With three ubiquitinases, ubiquitin is bound to the lysine residues of substrate proteins and consumes ATP as energy

A.Espitia-RangelE.Rodrguez-ArvaloI.Snchez-SeguraL.Martnez-GallardoN