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Laboratory tests revealed no significant abnormalities (Table 3)

First, there is an urgent need for region-specific treatment guidelines that emphasize the short-term use of corticosteroids followed by the transition to maintenance therapy [36]

It was previously proposed that the zonulin pathway is activated through direct binding of zonulin to EGFR, transactivation of EGFR through PAR2 activation, or a combination of both mechanisms (30)

Research on ALA and ALC often occurs at higher doses or in specific populations (e.g., older adults, clinical trials)

Our previous work also addressed the role of fibroblast-like synoviocytes (FLS) in AMPK signaling during KOA, accordingly suggesting that these cells promote both the onset and the progression of synovitis by regulating AMPK Signaling [23]