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Final results of a phase 2, open-label study of indisulam, idarubicin, and cytarabine in patients with relapsed or refractory acute myeloid leukemia and high-risk myelodysplastic syndrome

Every batch verified 99% pure by RP-HPLC and identity-confirmed by LC-MS

Li XM, Huang CK, Zhang TF, Teper AA, Srivastava K, Schofield BH, et al

Metabolic profiling Extraction and analysis of polar metabolites were performed as previously described 90,91 , with some modifications: 100 L of plasma were mixed with 1 mL of a pre-cooled (-20 C) homogenous methanol (MetOH):methyl-tert-butyl-ether (MTBE) 1:3 (v/v) mixture

Sies H, Klotz L-O, Sharov VS, Assmann A, Briviba K