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Szumlinski, K

The potential to counteract these effects has been demonstrated with IL-1 receptor antagonists, which have been shown to improve glucose tolerance and enhance insulin production [571]

Clinical research on probiotic efficacy generally uses doses in the tens of billions of CFU range

For in vivo experiments, the closest model would be the C57BL/6 mouse strain though degree of liver injury can vary between sub-strains without change in mechanism