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Imbalances in these systems are associated with depression, anxiety, attention difficulties, and various neurological conditions

Precision nutrition paradigms that consider genetic polymorphisms, metabolomic profiles, inflammatory biomarkers, and microbiome analyses could facilitate the identification of cardiometabolic phenotypes most likely to derive benefits from specific redox modulators

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Upon ferroptosis induction, NRF2 activation leads to increased CHAC1 expression, contributing to the degradation of GSH and facilitating ferroptotic cell death