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We hypothesize that this conversion of HepG2 line to hepatocyte-like cells was caused by factors such as cytokines or chemokines in the serum stimulating the expression of liver-specific transcription factors including CEBPA and CEBPB

Specifically, a 1 10 7 dose may be more appropriate for severe periodontitis, whereas lower doses could be more effective in mild to moderate cases

All samples were stored in a 80 C freezer

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