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Firstly, adipose tissue leads to the secretion of pro-inflammatory cytokines and adipokines, such as TNF-, IL-6, and leptin, thereby creating a TME conducive to cancer progression and metastasis (Liu X

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A Comprehensive Review of Immunotherapy Clinical Trials for Metastatic Urothelial Carcinoma: Immune Checkpoint Inhibitors Alone or in Combination, Novel Antibodies, Cellular Therapies, and Vaccines