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For C37 Fab molecules, only the VH/VL region bound to the E1E2 heterodimer in an identical manner, while the CH1/CL region exhibited varying degrees of swing relative to the VH/VL region, presumably to accommodate as many Fab molecules as possible at the 5f and 2f vertices

10.3390/ijms251910319 Int J Mol Sci

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LNPs with 30% -sitosterol and 10% cholesterol demonstrated the highest mRNA expression and were defined as LNP