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However, routine high-dose antioxidant therapy is not universally endorsed, as highlighted by the 2016 ASPEN-SCCM and 2019 ESPEN critical care nutrition guidelines, which caution against such interventions unless specific deficiencies are documented emphasizing the need for personalized approaches based on patient-specific needs [17,18]

Endosomal escape cell-penetrating peptides significantly enhance pharmacological effectiveness and CNS activity of systemically administered antisense oligonucleotides

PMID: 18815398

(2019) reported that mitophagy declines in the late stages of diabetic retinopathy (DR) and is decoupled from mitochondrial biogenesis during the progression of the disease

they all reflect the new character of the cell: its cancerishness