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While Raman spectra allowed no clear observation of the disulphide cleavage due to the characteristic peak of (S-S) overlapping strongly with the (S-N) peak, MS enabled for a clear distinction between the two species

Hepatic fibrogenesis Iron-induced liver cell injury results in the release of cell damage-associated cytokines, chemokines, and proinflammatory mediators, which leads to hepatic inflammation [84], the activation of hepatic stellate cells into pathological collagen-producing myofibroblasts, and ultimately hepatic fibrosis, cirrhosis, and liver cancer [77]

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Finally, greater understanding of the mechanisms of cell death will enable the application of novel radiosensitisers (Moding et al., 2016)