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Journal of neurophysiology , 86 (2), 629-640

Owing to the retrospective nature of this study, the requirement for informed consent was waived by the IRB of Gangnam Severance Hospital

Mechanistically, Dmrta2 has been shown to bind to telencephalic enhancers of the Pax6 and Gsx2 loci and repress their expression (Konno et al., 2019)

The result looks like accelerated aging

More and more evidence shows that mitochondria promote the initiation and development of ferroptosis through environmentally sensitive metabolic pathways (Chen et al., 2021a) A variety of mitochondrial metabolic pathways participate in the process of triggering ferroptosis