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During the preparation of this work the authors used the following tools: chatGPT5.2 (for the structuring the article, references collection and management), Gemini (for initial fill in the content), Perplexity Pro (for the expanding of each chapter of the article, addition of state-of-the-art references, emphasize the scientific depth of the review and generate images and tables summarizing the key ideas)

Factors Affecting Price: Treatment area, depth of resurfacing, number of sessions, and technology used influence the overall cost

Picture of Glutathione Figure 2

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COXs are abundantly expressed in neurons and microglia across various animal species ( in vivo and in vitro experimental showed that tumor necrosis factor- (TNF-)-mediated BBB breakdown is linked to COXs up-regulation the expression and activity of matrix metalloproteinases (MMPs) (Sugimoto et al., 2009)