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In this study, JNK and p38 MAPK pathways were activated through hsa-let-7c low-expression and IGF-1R over-expression, suggesting that the activation of this pathway is associated with IGF-1/IGF-1R/ hsa-let-7c axis (Fig

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Thus, attaining the balance between autophagy and apoptosis, via enhancing autophagy and/or suppressing apoptosis, is a mainstay target for the amelioration of ADHD