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No noticeable effect: in research terms, FOXO4-DRI only acts where senescent cells are present, and degraded or mislabeled product loses activity

It should be noted that eryptotic RBCs are cleared from the circulation in an efferocytosis-dependent fashion within minutes, in contrast to senescent erythrocytes [77], which require days to be engulfed by macrophages and cleared [72]

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Although the activity of this mutant was about one order of magnitude lower than that of native GPx3, the expression level of rhGPx3 mutant in E