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doi: 10.1080/10715760902736275 181 KeelMTrentzO

Once inside the cell, organic macromolecules undergo thousands of chemical reactions, known as cellular metabolism, which are facilitated by cellular enzymes

Preclinical models demonstrate 6080% tumor growth inhibition in KRAS-mutated NSCLC with minimal systemic toxicity, underscoring the therapeutic window created by tumor-selective copper accumulation [126]