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Description

10.1073/pnas.79.3.729

The phosphoglycerate dehydrogenase ( PHGDH ), which diverts another glycolytic intermediate for serine and glycine biosynthesis and redox NADH metabolite was rather less abundant

References Mithfer, A

Its therapeutic value is primarily demonstrated in two aspects: significantly improving dyskinetic symptoms, and effectively prolonging "on" time while shortening "off" time