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Using an interdisciplinary research approach, the aim is to identify mechanistic factors, acting alone and in combination, which impact aging and cancer risk, with the ultimate goal of designing and developing targeted prevention strategies

By coupling brain-targeted nanocarriers with patient-specific metabolic fingerprints, a gene-matched, pathway-matched strategy is emergingpositioning riboflavin at the center of personalized, systems-level interventions for both rare flavoproteinopathies and common neurodegenerative disorders

Statistical significance was evaluated using analysis of variance or MannWhitney's U -test

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