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Description

A.Hartley-WhitakerJ

37 (9), e23420 (2023)

The -secretase-derived C-terminal fragment of APP, C99, but not A, is a key contributor to early intraneuronal lesions in triple-transgenic mouse hippocampus

A total of 137 metabolites were detected following the data pre-processing involving deconvolution, blank filtering, exclusion of internal deuterated standards (lysine, glycine and succinic acid), elimination of false positive peaks, and QC filtering (removing mass features showing significant deviation within QC samples and RSD% values exceeding 25%)