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1 H NMR (500 MHz, DMSO) 0.09 (s, 27H), 0.38-0.44 (m, 2H), 1.21-1.25 (m, 2H), 1.35-1.42 (m, 2H), 1.50-1.55 (m, 2H), 1.71-1.75 (m, 2H), 2.05-2.08 (m, 2H), 2.97-3.00 (m, 2H), 3.01 (s, 9H), 3.11-3.14 (m, 2H)

Because of these factors, many early studies suggested that oral supplementation did very little to raise systemic levels

However, a study illustrated that the favorable effects of CoQ10 (400 mg/d) on migraine patients will be enhanced when used as an adjunct therapy in combination with other drugs, compared with using CoQ10 as monotherapy (169)