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Furthermore, multiple studies have confirmed that aggravated inflammation and accelerated glycolysis are tightly implicated in RA

4 ) (Felix et al ., 1999)

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For example, amphiphilic gold nanoparticles coated with hexanethiol and 11-mercaptoundecanesulfonic acid was used for the delivery of TLR7 ligands, as an immune stimulant for tumor lymph nodes, which can cause local immune activation and stimulate cytotoxic T cells to respond to tumors [74]