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Metallothionein-1 (MT-1) mRNA levels were markedly elevated during exacerbations in gout patients, particularly in PBMCs from patients with gouty stones

Reduced activity and depletion of NAD+ further attenuate protective function of Sirtuin [23, 24]

Therefore, accurate measurement of both reduced and oxidized forms of Glutathione is essential in research areas such as toxicology, pharmacology, and the study of various diseases where oxidative stress plays a role

Lipid peroxidation of biomembranes is one of the principal degenerative effects of free radicals

In line with our findings, a previous animal study reported a lower antioxidant capacity during aging in male rat brains than in female rat brains 57