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Herein, this study aims to develop an inhibitor to reduce dTTP and dCTP pools without general toxicity as an option for CML treatment

The ubiquitin-proteasome pathway is required for processing the NF-kappa B1 precursor protein and the activation of NF-kappa B Cell 1994 78 : 773785 Grisham MB, Palombella VJ, Elliott PJ, Conner EM, Brand S, Wong HL, Pien C, Mazzola LM, Destree A, Parent L, Adams J