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Description

CJC-1295 (no DAC) activates GHRH receptors (GHRH-R) on pituitary somatotrophs, while ipamorelin activates Growth Hormone Secretagogue Receptor 1a (GHSR-1a)

Regulatory note: The FDA added injectable GHK-Cu to a high-risk compounded substance list in September 2023

Mol Cancer Ther

Reviewer #1 The present manuscript describes the role of the GHSR in intracellular signaling on its own and in a variety of molecular interactions with other receptors as well as the potential for stimulation of GHSRs as a therapeutic target for a wide-range of clinical conditions