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Description

After SAM donates a methyl group, it becomes S-adenosylhomocysteine, or SAH

Maintaining sufficient glutathione stores protects hepatocytes from oxidative stress and supports efficient detoxification

Stem Cells 30, 372378

Integrating ChIP-seq, HiC, and PRO-seq datasets, we revealed broad functional binding of NRF2 at enhancer elements, including NRF2-dependent enhancer-derived RNA (eRNA) synthesis and extensive linkages between NRF2 target promoters and enhancers