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Zang C, Guth D, Bruno AM, Xu Z, Li H, Ammar N, Chew R, Guthe N, Hadley E, Kaushal R, Love T, McGrath BM, Patel RC, Seibert EC, Senathirajah Y, Singh SK, Wang F, Weiner MG, Wilkins KJ, Zhang Y, Metz TD, Hill E, Carton TW Nature communications

Reagents such as dimethyl sulfoxide (DMSO) and dimethyl-KG were purchased from Sigma Aldrich (St

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During ischemia, overstimulation of NMDA receptors by glutamate and glycine triggers pathological calcium influx, leading to mitochondrial calcium overload and subsequent mitochondrial permeability transition pore (mPTP) opening, further initiating apoptotic cascades [144] (Fig

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