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Human exposure to trichloroethylene is associated with increased variability of blood DNA methylation that is enriched in genes and pathways related to autoimmune disease and cancer

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In this pathway, phosphatidylethanolamine N-methyltransferase (PEMT) catalyzes the methylation of phosphatidylethanolamine to produce phosphatidylcholine, utilizing S-adenosylmethionine (SAM) as a methyl donor