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Discussion Numerous studies have documented that HFD in rats induces insulin resistance, while low-dose STZ administration selectively impairs insulin secretion, replicating the progressive nature of T2DM

Sci Rep 10 , 7283 (2020)

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Hence, the SARS-CoV-2 virus may evolve into variants with increased transmissibility and greater immune evasion potential than those existing variants of concern, consequently damaging the efficacy of current vaccines and drugs