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H., Kim H

In autoimmune patients, similar activation of Tregs with low dose IL-2 results in only transient activation of IL-2R signaling due to a defect in the inhibition of IL-2R desensitization, resulting in reduced pSTAT5 and DEPTOR degradation and loss of the Treg phenotype ( Figure 4 )

Jar Material / Color: In an effort to use more appropriate materials for certain products, we will be phasing in different bottles that contain HDPE vs PET