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456 Deficiencies in the tyrosine metabolic enzyme 4-hydroxyphenylpyruvate dioxygenase (HPD) lead to mTOR activation, promoting the accumulation of TCA cycle intermediates, such as citrate, -KG, succinate, fumarate, and malate

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It is a kind of compound containing sulfhydryl group (-SH), which widely exists in animal tissue, plant tissue, microorganism, and yeast

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Betaine treatment decreased oxidative stress, inflammation, and stellate cell activation in rats with alcoholic liver fibrosis

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