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Corticosteroids: dexamethasone Dexamethasone, a well-researched alternative for those intolerant of or contraindicated with acetazolamide, effectively prevents AMS/HACE despite not facilitating acclimatization as effectively as acetazolamide

Additionally, although primarily exhaled, acetone may be metabolized into usable energy sources such as pyruvate, lactate and acetate

The mammalian drug biotransformation systems are thought to have first evolved from the need to detoxify and eliminate plant and bacterial bioproducts and toxins, which later extended to drugs and other environmental xenobiotics

Zinc Zinc is an essential nutrient mineral that acts as a catalytic agent for over 300 separate enzymatic reactions in the body (Higdon 2013b)

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